Deadline bring word that Rooney Mara (The Girl with the Dragon Tattoo) has replaced Blake Lively in Steven Soderbergh’s forthcoming thriller ‘Side Effects,’ joining Catherine Zeta-Jones, Jude Law and Channing Tatum. Mara plays Emily Hawkins, a sexy but unsettled young woman who is taking serious amounts of prescription drugs to deal with anxiety and depression surrounding the pending release of her husband from prison (Tatum). This leads her into an affair with a doctor (Law).

The Scott Z. Burns (The Informant!, Contagion) scripted film is being financed by Megan Ellison’s Annapurna Pictures, with production to start in April. ’Side Effects’ will mark Mara’s first film with Soderbergh. The thriller is Tatum’s third collaboration with the director (Haywire and Magic Mike) and Law’s second (Contagion). Soderbergh’s latest film, ‘Haywire,’ is out in cinemas now. His next movie, ‘Magic Mike,’ is released in the summer.